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Guttridge, Denis
One or more keywords matched the following items that are connected to Guttridge, Denis
Item TypeName
Concept Body Mass Index
Concept Protein Binding
Concept I-kappa B Kinase
Concept Mice, Inbred mdx
Concept Brain Neoplasms
Concept DNA-Binding Proteins
Concept Amyloid beta-Protein Precursor
Concept Transforming Growth Factor beta
Concept NF-kappa B
Concept Animals, Newborn
Concept Aged, 80 and over
Concept Heterozygote
Concept Bone and Bones
Concept Mice, Inbred BALB C
Concept Body Weight
Concept Benzimidazoles
Concept Dependovirus
Concept Cricetinae
Concept Biomarkers, Tumor
Concept Dogs
Concept Animals
Concept Blotting, Northern
Concept Aged
Concept Proto-Oncogene Proteins c-bcl-2
Concept Protein Biosynthesis
Concept GTP-Binding Protein alpha Subunits, G12-G13
Concept Mice, Knockout
Concept Mice, Inbred C3H
Concept NF-kappa B p50 Subunit
Concept Adolescent
Concept Blotting, Western
Concept Bone Neoplasms
Concept Cricetulus
Concept Rats, Inbred BN
Concept Biomarkers
Concept Mice
Concept Bone Marrow Cells
Concept Models, Biological
Concept Research Personnel
Concept Behavior, Animal
Concept Receptors, Adrenergic, beta
Concept Adult
Concept Mice, Inbred C57BL
Concept Bone Morphogenetic Proteins
Concept Boronic Acids
Concept Computational Biology
Concept Mice, Transgenic
Concept Herpesvirus 4, Human
Concept Biomechanical Phenomena
Concept Paired Box Transcription Factors
Concept Bone Resorption
Concept Humans
Concept Child
Concept beta Catenin
Concept SKP Cullin F-Box Protein Ligases
Concept Mice, Inbred NOD
Concept Blood Glucose
Concept Binding Sites
Concept Rats, Inbred F344
Concept Mice, Nude
Concept Adenoviridae
Concept Mice, SCID
Concept Mice, Inbred Strains
Concept CCAAT-Enhancer-Binding Proteins
Concept Rats
Concept I-kappa B Proteins
Concept Breast Neoplasms
Concept B-Lymphocytes
Concept Middle Aged
Concept Rats, Sprague-Dawley
Concept Sendai virus
Concept Mice, Inbred DBA
Concept Genetic Vectors
Concept Interinstitutional Relations
Concept Epstein-Barr Virus Infections
Concept Young Adult
Concept Bone Morphogenetic Protein 2
Concept Bone Morphogenetic Protein 4
Concept Leukemia, Lymphocytic, Chronic, B-Cell
Concept Blood Proteins
Concept Base Sequence
Concept Zebrafish
Concept HIV
Concept Body Composition
Concept RNA-Binding Proteins
Concept NF-kappa B p52 Subunit
Concept Trypan Blue
Academic Article TNF inhibits Notch-1 in skeletal muscle cells by Ezh2 and DNA methylation mediated repression: implications in duchenne muscular dystrophy.
Academic Article MyoD Regulates Skeletal Muscle Oxidative Metabolism Cooperatively with Alternative NF-?B.
Academic Article An NF-?B--EphrinA5-Dependent Communication between NG2(+) Interstitial Cells and Myoblasts Promotes Muscle Growth in Neonates.
Academic Article NF-?B-mediated Pax7 dysregulation in the muscle microenvironment promotes cancer cachexia.
Academic Article IKKa and alternative NF-?B regulate PGC-1? to promote oxidative muscle metabolism.
Academic Article NF-?B negatively impacts the myogenic potential of muscle-derived stem cells.
Academic Article NF-?B signaling in skeletal muscle health and disease.
Academic Article NF-kappaB signaling: a tale of two pathways in skeletal myogenesis.
Academic Article NF-kappaB functions in stromal fibroblasts to regulate early postnatal muscle development.
Academic Article The RelA/p65 subunit of NF-kappaB specifically regulates cyclin D1 protein stability: implications for cell cycle withdrawal and skeletal myogenesis.
Academic Article NF-kappaB-YY1-miR-29 regulatory circuitry in skeletal myogenesis and rhabdomyosarcoma.
Academic Article Skeletal muscle diseases, inflammation, and NF-kappaB signaling: insights and opportunities for therapeutic intervention.
Academic Article IKK/NF-kappaB regulates skeletal myogenesis via a signaling switch to inhibit differentiation and promote mitochondrial biogenesis.
Academic Article NF-kappaB regulation of YY1 inhibits skeletal myogenesis through transcriptional silencing of myofibrillar genes.
Academic Article Thrombin causes a marked delay in skeletal myogenesis that correlates with the delayed expression of myogenin and p21CIP1/WAF1.
Academic Article Requirement for NF-?B in maintenance of molecular and behavioral circadian rhythms in mice.
Academic Article NF-?B inhibition rescues cardiac function by remodeling calcium genes in a Duchenne muscular dystrophy model.
Academic Article Chemotherapy-induced muscle wasting: association with NF-?B and cancer cachexia.
Academic Article Classical NF-?B Metabolically Reprograms Sarcoma Cells Through Regulation of Hexokinase 2.
Academic Article SAMHD1 suppresses innate immune responses to viral infections and inflammatory stimuli by inhibiting the NF-?B and interferon pathways.
Academic Article NF-?B regulates GDF-15 to suppress macrophage surveillance during early tumor development.
Academic Article NF?B signaling in alveolar rhabdomyosarcoma.
Academic Article Dissection of the Major Hematopoietic Quantitative Trait Locus in Chromosome 6q23.3 Identifies miR-3662 as a Player in Hematopoiesis and Acute Myeloid Leukemia.
Academic Article Dietary Apigenin Exerts Immune-Regulatory Activity in Vivo by Reducing NF-?B Activity, Halting Leukocyte Infiltration and Restoring Normal Metabolic Function.
Academic Article NF-?B functions in tumor initiation by suppressing the surveillance of both innate and adaptive immune cells.
Academic Article Microglia induce motor neuron death via the classical NF-?B pathway in amyotrophic lateral sclerosis.
Academic Article miR-29 acts as a decoy in sarcomas to protect the tumor suppressor A20 mRNA from degradation by HuR.
Academic Article Regulation of skeletal muscle oxidative phenotype by classical NF-?B signalling.
Academic Article Reining in nuclear factor-kappaB in skeletal muscle disorders.
Academic Article NF-?B inhibition delays DNA damage-induced senescence and aging in mice.
Academic Article IKKa-mediated signaling circuitry regulates early B lymphopoiesis during hematopoiesis.
Academic Article Detection of NF-?B activity in skeletal muscle cells by electrophoretic mobility shift analysis.
Academic Article Oral resveratrol therapy inhibits cancer-induced skeletal muscle and cardiac atrophy in vivo.
Academic Article Systemic delivery of NEMO binding domain/IKK? inhibitory peptide to young mdx mice improves dystrophic skeletal muscle histopathology.
Academic Article Improvement of cardiac contractile function by peptide-based inhibition of NF-?B in the utrophin/dystrophin-deficient murine model of muscular dystrophy.
Academic Article Peptide-based inhibition of NF-?B rescues diaphragm muscle contractile dysfunction in a murine model of Duchenne muscular dystrophy.
Academic Article Inhibition of the IKK/NF-?B pathway by AAV gene transfer improves muscle regeneration in older mdx mice.
Academic Article Zinc modulates the innate immune response in vivo to polymicrobial sepsis through regulation of NF-kappaB.
Academic Article RelA/p65 functions to maintain cellular senescence by regulating genomic stability and DNA repair.
Academic Article Epigenetic changes during disease progression in a murine model of human chronic lymphocytic leukemia.
Academic Article Apigenin blocks lipopolysaccharide-induced lethality in vivo and proinflammatory cytokines expression by inactivating NF-kappaB through the suppression of p65 phosphorylation.
Academic Article Biomechanical signals suppress TAK1 activation to inhibit NF-kappaB transcriptional activation in fibrochondrocytes.
Academic Article Interplay of IKK/NF-kappaB signaling in macrophages and myofibers promotes muscle degeneration in Duchenne muscular dystrophy.
Academic Article ASC directs NF-kappaB activation by regulating receptor interacting protein-2 (RIP2) caspase-1 interactions.
Academic Article RelA/p65 regulation of IkappaBbeta.
Academic Article Signaling pathways weigh in on decisions to make or break skeletal muscle.
Academic Article NF-kappa B and I kappa B alpha are found in the mitochondria. Evidence for regulation of mitochondrial gene expression by NF-kappa B.
Academic Article Tumor necrosis factor-regulated biphasic activation of NF-kappa B is required for cytokine-induced loss of skeletal muscle gene products.
Academic Article Suppression of tumor necrosis factor-mediated apoptosis by nuclear factor kappaB-independent bone morphogenetic protein/Smad signaling.
Academic Article Inhibition of NF-kappa B activity by thalidomide through suppression of IkappaB kinase activity.
Academic Article NF-kappaB-induced loss of MyoD messenger RNA: possible role in muscle decay and cachexia.
Academic Article Selective activation of NF-kappa B subunits in human breast cancer: potential roles for NF-kappa B2/p52 and for Bcl-3.
Academic Article Akt suppresses apoptosis by stimulating the transactivation potential of the RelA/p65 subunit of NF-kappaB.
Academic Article NF-kappaB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis.
Academic Article IkappaBalpha gene transfer is cytotoxic to squamous-cell lung cancer cells and sensitizes them to tumor necrosis factor-alpha-mediated cell death.
Academic Article NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1.
Academic Article The effect of altered Toll-like receptor 4 signaling on cancer cachexia.
Academic Article Protease nexin-1, a thrombin inhibitor, is regulated by interleukin-1 and dexamethasone in normal human fibroblasts.
Academic Article Characterization of the human protease nexin-1 promoter and its regulation by Sp1 through a G/C-rich activation domain.
Academic Article Wnt-1 signaling inhibits apoptosis by activating beta-catenin/T cell factor-mediated transcription.
Academic Article Wnt signaling promotes oncogenic transformation by inhibiting c-Myc-induced apoptosis.
Academic Article Role for activating transcription factor 3 in stress-induced beta-cell apoptosis.
Academic Article Dystrophin glycoprotein complex dysfunction: a regulatory link between muscular dystrophy and cancer cachexia.
Academic Article Assessment of tumor necrosis factor alpha blockade as an intervention to improve tolerability of dose-intensive chemotherapy in cancer patients.
Academic Article Transcriptional regulation of parathyroid hormone-related protein promoter P2 by NF-kappaB in adult T-cell leukemia/lymphoma.
Academic Article Epstein-Barr virus-encoded dUTPase enhances proinflammatory cytokine production by macrophages in contact with endothelial cells: evidence for depression-induced atherosclerotic risk.
Academic Article Comparison of animal models for head and neck cancer cachexia.
Academic Article IFN-alpha and bortezomib overcome Bcl-2 and Mcl-1 overexpression in melanoma cells by stimulating the extrinsic pathway of apoptosis.
Academic Article Bortezomib reverses a post-translational mechanism of tumorigenesis for patched1 haploinsufficiency in medulloblastoma.
Academic Article A novel role for IkappaBzeta in the regulation of IFNgamma production.
Academic Article Using transcriptomics to identify and validate novel biomarkers of human skeletal muscle cancer cachexia.
Academic Article Mass spectrometric detection of candidate protein biomarkers of cancer cachexia in human urine.
Academic Article IL-4R drives dedifferentiation, mitogenesis, and metastasis in rhabdomyosarcoma.
Academic Article Myeloid-derived suppressor cell inhibition of the IFN response in tumor-bearing mice.
Academic Article Making muscles grow by g protein-coupled receptor signaling.
Academic Article M-CSF induces monocyte survival by activating NF-?B p65 phosphorylation at Ser276 via protein kinase C.
Academic Article Loss of miR-29 in myoblasts contributes to dystrophic muscle pathogenesis.
Academic Article MyoD-dependent regulation of NF-?B activity couples cell-cycle withdrawal to myogenic differentiation.
Academic Article Cancer cachexia: mediators, signaling, and metabolic pathways.
Academic Article Retraction: MyoD-dependent regulation of NF-?B activity couples cell-cycle withdrawal to myogenic differentiation.
Academic Article Expression of cancer-testis antigens MAGEA1, MAGEA3, ACRBP, PRAME, SSX2, and CTAG2 in myxoid and round cell liposarcoma.
Academic Article Metabolomic profiling reveals severe skeletal muscle group-specific perturbations of metabolism in aged FBN rats.
Academic Article Modeling human cancer cachexia in colon 26 tumor-bearing adult mice.
Academic Article Inflammation based regulation of cancer cachexia.
Academic Article Evaluating potential biomarkers of cachexia and survival in skeletal muscle of upper gastrointestinal cancer patients.
Academic Article Impaired regeneration: A role for the muscle microenvironment in cancer cachexia.
Academic Article Inflammation induced loss of skeletal muscle.
Academic Article Preclinical Investigation of the Novel Histone Deacetylase Inhibitor AR-42 in the Treatment of Cancer-Induced Cachexia.
Academic Article A TGF-? pathway associated with cancer cachexia.
Academic Article Serine/Threonine Kinase MLK4 Determines Mesenchymal Identity in Glioma Stem Cells in an NF-?B-dependent Manner.
Academic Article The Bromodomain BET Inhibitor JQ1 Suppresses Tumor Angiogenesis in Models of Childhood Sarcoma.
Academic Article ?Np63 mediates cellular survival and metastasis in canine osteosarcoma.
Academic Article Analysis of Aerobic Respiration in Intact Skeletal Muscle Tissue by Microplate-Based Respirometry.
Academic Article Dual Inhibition of MEK and PI3K/Akt Rescues Cancer Cachexia through both Tumor-Extrinsic and -Intrinsic Activities.
Academic Article Enhancing the Cell Permeability and Metabolic Stability of Peptidyl Drugs by Reversible Bicyclization.
Academic Article Predictors of Pancreatic Cancer-Associated Weight Loss and Nutritional Interventions.
Academic Article Evaluation of patritumab with or without erlotinib in combination with standard cytotoxic agents against pediatric sarcoma xenograft models.
Academic Article Perioperative cytokine levels portend early death after pancreatectomy for ductal adenocarcinoma.
Academic Article Dysregulated Myogenesis in Rhabdomyosarcoma.
Academic Article Cancer-associated cachexia.
Academic Article Circulating interleukin-6 is associated with disease progression, but not cachexia in pancreatic cancer.
Academic Article The RNA demethylase FTO is required for maintenance of bone mass and functions to protect osteoblasts from genotoxic damage.
Academic Article Correction: Wnt signaling promotes oncogenic transformation by inhibiting c-Myc-induced apoptosis.
Concept Laboratory Personnel
Concept Solid-Phase Synthesis Techniques
Concept CCCTC-Binding Factor
Concept Forkhead Box Protein O1
Concept Bortezomib
Concept NF-KappaB Inhibitor alpha
Academic Article Identification of circulating plasma ceramides as a potential sexually dimorphic biomarker of pancreatic cancer-induced cachexia.
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  • NF
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